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What works in clinical validity
How researchers get from one idea to prove the clinical validity?
The idea of what may work may come from a lab test. There may be animal testing. Research into patients also generates important knowledge and theory.
However, none of these types of studies provide definitive evidence that a particular treatment is effective. Many other factors may affect treatment at the same time. People often improve with or without treatment.
Put ideas, theories and beliefs in the test
Testing for clinical validity in humans requires experimentation to indicate the true effect of a particular behavior. This is why the possible effects of treatment and prevention methods need to be studied in clinical trials.
A trial is difficult to provide a clear answer. Later tests sometimes confirm early results - sometimes conflicting results. So the researchers searched for and then analyzed all the trials that looked at the specific problem. This type of research is called systematic review. It can be used to look for research other than research and address other issues such as "What causes the disease?"
Determine the area of answer and uncertainty
A systematic review shows which treatments and preventions have been proven - and what is not yet known. Clarifying what is definite or uncertain is an important part of informed decision making.
Systematic reviews are often referred to as evidence based medicine or healthcare. They are very important for areas that point out the need for more research.
Other names for such studies are "evidence synthesis", "comparative effectiveness assessment" and "health technology assessment."